Nicotine is one of the
most common and addictive substances found in today’s society. Close to half a million
people die from smoking-related illnesses in the United States each year, accumulating
more deaths from smoking than motor vehicle crashes, drug abuse, AIDS, suicide,
and homicide combined
(CDC, 2008).
This mild stimulant sends
a jolt of adrenaline through the blood stream that provides the “buzz” that smokers
experience. Within two to three hours
the subject will begin to have signs of cigarette withdraw. Scientists have long known that certain areas
of the brain are responsible for cravings and impulsive behavior. The
orbitofrontal cortex of the brain is responsible for deciding a level of
determination towards a behavior. In this case the brains appraisal of need for
a cigarette. The prefrontal cortex is responsible for planning complex
cognitive behavior and decision making.
Findings from the National
Academy of Sciences, suggest that both the orbitofrontal cortex
and the prefrontal cortex (PFC) were key respondents to cigarette cravings. The
scientists focused on these two parts of the brain that could be manipulated to
change the occurring behavior of cravings in smokers. They scanned the brains
of ten participants that were heavy smokers using functional Magnetic Resonance
Imaging (fMRI)(that track the amount of blood flow through the brain) to see
how these spots reacted when the person watched videos of cigarette smoking.
Their brains showed increased brain activity while watching videos of smokers
than opposed to the neutral videos watched. Those who were allowed to smoke
immediately after the demonstration recorded greater cravings and their brains
showed more activity in the PFC than those who were told they had to wait four
hours before they could have a cigarette.
Researchers have developed a method to try and reduce cravings in smokers. Scientists used Transcranial Magnetic
Stimulation (TMS) to send a weak electrical current to certain areas of the
brain. They were able to stimulate as well as suppress activity. When subjects
watched the smoking videos again after TMS the reactions were identical to the neutral
videos and showing less cravings in both groups.
As a smoker I experience
cravings continuously throughout the day. Quitting is something very close to
mind but with its easy accessibility and my frequent exposure, the habit is
hard to kick. For years I’ve thought people who were trying to quit smoking
cigarettes should be able to be hospitalized the same way a person would be
helped with withdraw from alcohol and heroin. This research into non-invasive
techniques and brain stimulation might be a practical way to help addicts break
destructive habits.
Works Cited:
Centers for Disease
Control and Prevention (CDC). (2008).
Annual smoking attributable mortality, years of
potential life lost, and economic costs- Untied
States,2000-2004. Morbidity
and Mortality Weekly
Report, 57(45), 1226-1228
Lewis, T. (2013, Jan 28).
Brain Chemistry Circuitry
behind
cigarette craving revealed. Scientific American.
How is this magnetic stimulation delivered? In an MRI machine, or through a smaller device?
ReplyDeleteBravo!
They implanted electrodes on the scalp of the head and delivered a small electrical current to certain parts of the brain. (Similar to an EEG)
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